Humanization of medicine
نویسندگان
چکیده
منابع مشابه
Humanization of antibodies.
Humanization has played a fundamental role in the remarkable progress of antibodies as therapeutic reagents. Here we have reviewed the publications on antibody humanization since the first report on CDR grafting in the second half of the 1980's up to June 2007. We describe the two main trends in the field: rational and empirical methods to humanize antibodies. Rational methods rely on the so-ca...
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BACKGROUND AND OBJECTIVES This study aims to describe the view of family members about the quality of care given in a general intensive care unit of a university hospital. METHODS A questionnaire to evaluate the level of satisfaction with the care was elaborated. The study included family members of patients with a length of stay more than 48h who already had visited the patient one time or m...
متن کاملhumanization of health care technology
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متن کاملAntibody Humanization Techniques
Antibodies are proteins with very important functions in the immune system. Thanks to their ability to recognize specific sequences from pathogens and other threats, antibodies can participate in the recognition and removal of foreign threats, such as virus and bacteria (Janeway et al.). Every human body is able to create millions of slightly different antibodies; every antibody has the ability...
متن کاملTabhu: tools for antibody humanization
SUMMARY Antibodies are rapidly becoming essential tools in the clinical practice, given their ability to recognize their cognate antigens with high specificity and affinity, and a high yield at reasonable costs in model animals. Unfortunately, when administered to human patients, xenogeneic antibodies can elicit unwanted and dangerous immunogenic responses. Antibody humanization methods are des...
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ژورنال
عنوان ژورنال: Anales de la Facultad de Ciencias Médicas (Asunción)
سال: 2017
ISSN: 1816-8949
DOI: 10.18004/anales/2017.050(03)13-016